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Our research is focussed on

  • Lymphocyte interactions in vivo (Prof. Dr. Thomas Brocker)
  • Understanding how selection processes in the thymus generate a functional and self-tolerant T cell repertoire (Prof. Dr. Ludger Klein)
  • Molecular regulation of peripheral T cell activation, differentiation and effector function. One focus of our research is the control of gene expression on the posttranscriptional level (Prof. Dr. Vigo Heissmeyer)
  • Differentiation, plasticity and function of dendritic cell subpopulations, especially their role in antiviral immune defense and intestinal inflammation (Prof. Dr. Anne Krug)
  • Parameters of lymphocyte activation during an immune response in vivo (PD Dr. Reinhard Obst)
  • T follicular helper cells in T helper cell fate decisions, function, and plasticity (Dr. Dirk Baumjohann)
  • T-cell response in viral hepatitis B and C (PD Dr. Norbert Grüner)