Selected Publications

https://orcid.org/0000-0002-5801-0151

2025

Hamsa Narasimhan, Maria L. Richter, Ramin Shakiba, Nikos E. Papaioannou, Christina Stehle, Kaushikk Ravi Rengarajan, Isabel Ulmert, Arek Kendirli, Clara de la Rosa, Pin-Yu Kuo, Abigail Altman, Philipp Münch, Saba Mahboubi Vanessa Küntzel, Amina Sayed, Eva-Lena Stange, Jonas Pes, Alina Ulezko Antonova, Carlos-Filipe Pereira, Ludger Klein, Diana Dudziak, Marco Colonna, Natalia Torow, Mathias W. Hornef, Björn E. Clausen, Martin Kerschensteiner, Katharina Lahl, Chiara Romagnani, Maria Colomé-Tatché, and Barbara U. Schraml (2025 Feb 24) RORγt-expressing dendritic cells are functionally versatile and evolutionarily conserved antigen-presenting cells. PNAS 122 (9) e2417308122. https://doi.org/10.1073/pnas.241730812.

Johannes Woelk, Hamsa Narasimhan, Christa Pfeifhofer-Obermair, Barbara U. Schraml, Natascha Hermann-Kleiter (2025 Jan 07) NR2F6 regulates stem cell hematopoiesis and myelopoiesis in mice. Front. Immunol. Volume 15-2024. https://doi.org/10.3389/fimmu.2024.1404805

2024

Hongkui Xiao, Isabel Ulmert, Luisa Bach, Johanna Huber, Hamsa Narasimhan, Ilia Kurochkin, Yinshui Chang, Signe Holst, Urs Mörbe, Lili Zhang, Andreas Schlitzer, Carlos-Filipe Pereira, Barbara U. Schraml, Dirk Baumjohann & Katharina Lahl (2024 Apr 30) Genomic deletion of Bcl6 differentially affects conventional dendritic cell subsets and compromises Tfh/Tfr/Th17 cell responses. Nature Communications 15: 3554. https://doi.org/10.1038/s41467-024-46966-6. PMID: 38688934

2023

Hans Christian Probst, Patrizia Stoitzner, Lukas Amon, Ronald A. Backer, Anna Brand, Jianzhou Chen, Björn E. Clausen, Sophie Dieckmann, Diana Dudziak, Lukas Heger, Katrin Hodapp, Florian Hornsteiner, Avi-Hai Hovav, Lukas Jacobi, Xingqi Ji, Nadine Kamenjarin, Katharina Lahl, Imran Lahmar, Jelena Lakus, Christian H. K. Lehmann, Daniela Ortner, Marion Picard, Maria Paula Roberti, Lukas Rossnagel, Yasmin Saba, Carmen Schalla, Andreas Schlitzer, Barbara U. Schraml, Kristian Schütze, Anna Seichter, Kristin Seré, Athanasios Seretis, Sieghart Sopper, Helen Strandt, Martina M. Sykora, Hannah Theobald, Christoph H. Tripp, Laurence Zitvogel (2023 Nov) Guidelines for DC preparation and flow cytometry analysis of mouse nonlymphoid tissues. Eur J Immunol 53(11):e2249819. doi: 10.1002/eji.202249819. PMID: 36512638

Felix Bayerl, Philippa Meiser, Sainitin Donakonda, Anna Hirschberger, Sebastian B Lacher, Anna-Marie Pedde, Chris D Hermann , Anais Elewaut, Moritz Knolle, Lukas Ramsauer, Thomas J Rudolph , Simon Grassmann, Rupert Öllinger, Nicole Kirchhammer, Marcel Trefny, Martina Anton, Dirk Wohlleber Bastian Höchst, Anne Zaremba, Achim Krüger, Roland Rad, Anna C Obenauf, Dirk Schadendorf, Alfred Zippelius , Veit R Buchholz, Barbara U Schraml, Jan P Böttcher  (2023 Jun 13) Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell response. Immunity 56(6): 1341-1358.e11. doi: 10.1016/j.immuni.2023.05.011. PMID: 37315536

Barbara U Schraml (2023 Mar 31) Tuning sentinel immune cells. Science 379(6639):1301-1302. doi: 10.1126/science.adh2090. PMID: 36996196

2021

Salei N, Ji X, Pakalniškytė D, Kuentzel V, Rambichler S, Li N, Moser M, Steiger K, Buch T, Anders HJ, Schraml BU. (2021) Selective depletion of a CD64-expressing phagocyte subset mediates protection against toxic kidney injury and failure. Proc Natl Acad Sci USA. 2021 Sep 28;118(39):e2022311118. doi: 10.1073/pnas.2022311118. PMID: 34518373

Papaioannou, NE, Salei N, Rambichler S, Ravi K, Popovic J, Küntzel V, Lehmann CHK, Fiancette R, Salvermoser J, Gajdasik DW, Mettler R, Messerer D, Carrelha J, Ohnmacht C, Haller D, Stumm R, Straub T, Jacobsen SEW, Schulz C, Withers DR, Schotta G, Dudziak D, Schraml BU (2021) Environmental signals rather than layered ontogeny imprint the function of type 2 conventional dendritic cells in young and adult mice. Nature Communications 21, 464. https://www.nature.com/articles/s41467-020-20659-2. PMID: 33469015

2020

Salei N, Rambichler S, Salvermoser J, Papaioannou NE, Schuchert R, Pakalniškytė D, Na Li, Marschner JA, Lichtnekert J, Stremmel C, Cernilogar FM, Salvermoser M, Walzog B, Straub T, Schotta G, Anders HJ, Schulz C, Schraml BU (2020) The Kidney Contains Ontogenetically Distinct Dendritic Cell and Macrophage Subtypes throughout Development That Differ in Their Inflammatory Properties. Journal of the American Society of Nephrology, 31(2), 257-78. DOI: 10.1681/ASN.2019040419. PMID: 31932472

2019

Papaioannou NE, Pasztoi M, Schraml BU (2019) Understanding the Functional Properties of Neonatal Dendritic Cells: A Doorway to Enhance Vaccine Effectiveness? Front Immunol., 9: 553–8. doi: 10.3389/fimmu.2018.03123. PMID: 30687326

Salvermoser J, van Blijswijk J, Papaioannou NE, Rambichler S, Pasztoi M, Pakalniškyte D, Rogers NC, Keppler SJ, Straub T, Reis e Sousa C and Schraml BU (2018) Clec9a-Mediated Ablation of Conventional Dendritic Cells Suggests a Lymphoid Path to Generating Dendritic Cells In Vivo. Frontiers in Immunology. 9:563-15. DOI: 10.3389/fimmu.2018.00699. PMID: 29713321

2015

Böttcher JP, Zelenay S, Rogers NC, Helft J, Schraml BU and Reis e Sousa C (2015) Oncogenic transformation of dendritic cells and their precursors leads to rapid cancer development in mice. J Immunol. 195(10):5066-76. DOI: 10.4049/jimmunol.1500889. PMID: 26459350

Helft J, Böttcher J, Chakravarty P, Zelenay S, Huotari J, Schraml BU, Goubau D, Reis E Sousa C (2015) GM-Csf mouse bone marrow cultures comprise a heterogeneous population of CD11c(+)MHCII(+) Macrophages and Dendritic Cells. Immunity 16;42(6):1197-211. DOI: 10.1016/j.immuni.2015.05.018. PMID: 26084029

2014

van Blijswijk J, Schraml BU, Rogers NC, Whitney PG, Zelenay S, Acton SE, Reis e Sousa C (2014) Altered Lymph Node Composition in Diphtheria Toxin Receptor-Based Mouse Models to ablate Dendritic Cells. J Immunol. 94 (1), 307-315. DOI: 10.4049/jimmunol.1401999. PMID: 25411201

Guilliams M, Ginhoux F, Jakubzick C, Naik SH, Onai N, Schraml BU, Segura E, Tussiwand R, and Yona S (2014) Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny. Nat.Rev.Imm. Aug;14(8):571-8. DOI: 10.1038/nri3712. PMID: 25033907

2013

Schraml BU, van Blijswijk J, Zelenay S, Whitney PG, Filby A, Acton SE, Rogers NC, Moncaut N, Carvajal JJ, Reis e Sousa C (2013) Genetic tracing via expression history of DNGR-1 defines dendritic cells as a hematopoietic lineage. Cell, 154(4):843-858. DOI: 10.1016/j.cell.2013.07.014. PMID: 23953115

2011

Ise W, Kohyama M, Schraml BU, Zhang T, Schwer B, Basu U, Alt FW, Tang J, Oltz EM, Murphy TL, Murphy KM (2011) The transcription factor BATF controls the global regulators of class-switch recombination in both B and T cells. Nat Immunol. Jun;12(6):536-43. DOI: 10.1038/ni.2037. PMID: 21572431

2009

Schraml BU, Hildner K, Ise W, Lee WL, Smith WA, Solomon B, Sahota G, Sim J, Mukasa R, Cemerski S, Hatton RD, Stormo GD, Weaver CT, Russell JH, Murphy TL, Murphy KM (2009) Batf expands AP-1 target specificity to control TH17 differentiation. Nature. Jul 16;460(7253):405-9. doi: 10.1038/nature08114. PMID: 19578362

2008

Hildner K, Edelson BT, Purtha WE, Diamond M, Matsushita H, Kohyama M, Calderon B, Schraml BU, Unanue ER, Diamond MS, Schreiber RD, Murphy TL, Murphy KM (2008) BATF3 deficiency reveals a critical role for CD8+ dendritic cells in cytotoxic T cell immunity. Science. Nov 14;322(5904):1097-100. DOI: 10.1126/science.1164206. PMID: 19008445