Immunology
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Extracellular Vesicles

Extracellular vesicles (EVs) modulate immune responses, although there is still little direct evidence in vivo for such a mechanism. We develop novel methods and reagents to analyze cells associated with EVs in infected mice and humans. We focus on effector T cells and other PBMC which strongly bind Evs and study the capacities of EVs to drive T-cell-fate decisions.